Correlation between Sputum Bacterial Load and Disease Severity in Children with Chlamydia Trachomatis Pneumonia

Li Ying; Geng Gang; Dai Jihong

doi:10.13407/ j.cnki.jpp.1672-108X.2022.02.015

您当前的位置：

首页 >

文章列表页 >

Correlation between Sputum Bacterial Load and Disease Severity in Children with Chlamydia Trachomatis Pneumonia

更新时间：2022-11-03

- Correlation between Sputum Bacterial Load and Disease Severity in Children with Chlamydia Trachomatis Pneumonia
- Vol. 28, Issue 2, Pages: 49-51(2022)
- 作者机构：
  
  重庆医科大学附属儿童医院，儿童发育疾病研究教育部重点实验室，国家儿童健康与疾病临床医学研究中心，儿童发育重大疾病国家国际科技合作基地,重庆,400014
- 作者简介：
- 基金信息：
- DOI：10.13407/ j.cnki.jpp.1672-108X.2022.02.015
  CLC：
- Published：2022，
  
  Published Online：10 February 2022，
扫描看全文
Li Ying, Geng Gang, Dai Jihong. Correlation between Sputum Bacterial Load and Disease Severity in Children with Chlamydia Trachomatis Pneumonia. [J]. 28(2):49-51(2022)
DOI：

Li Ying, Geng Gang, Dai Jihong. Correlation between Sputum Bacterial Load and Disease Severity in Children with Chlamydia Trachomatis Pneumonia. [J]. 28(2):49-51(2022) DOI： 10.13407/ j.cnki.jpp.1672-108X.2022.02.015.

摘要

目的:探讨沙眼衣原体肺炎患儿痰载菌量与病情严重程度的相关性。方法:选取147例沙眼衣原体肺炎患儿为研究对象

采用荧光定量聚合酶链反应技术对标本中沙眼衣原体DNA 进行定量检测

根据检测结果分为低拷贝数组( <104 / mL)、中拷贝数组(104 ~106 / mL)和高拷贝数组(>106 / mL)

比较不同组别间的临床症状、胸片结果、呼吸机辅助呼吸时间及住院时间的差异

出院2 周后复查胸片

并与住院期间胸片结果进行比较。结果:气促时间比较

高拷贝数组与中、低拷贝数组之间差异有统计学意义(P<0.01)

中、低拷贝数组之间差异无统计学意义(P>0.05);热程比较

高拷贝数组与中拷贝数组(P<0.05)、低拷贝数组(P<0.01)之间差异有统计学意义

中、低拷贝数组之间差异无统计学意义(P>0.05);胸片结果比较

高拷贝数组与中、低拷贝数组之间差异有统计学意义(P<0.05)

中、低拷贝数组之间差异无统计学意义(P>0.05);住院时间比较

高拷贝数组与中、低拷贝数组之间差异有统计学意义(P<0.01)

中、低拷贝数组之间差异无统计学意义(P>0.05);3 组患儿呼吸机辅助呼吸时间及发热例数比较差异无统计学意义(P>0.05)。两周后胸片恢复情况均较好

3 组比较差异无统计学意义( P>0.05)。结论:沙眼衣原体肺炎痰中载菌量达到一定数量后与患儿气促时间、热程、胸片严重程度、住院时间等临床特征有一定相关性

但是预后较好。

Abstract

Objective: To probe into the correlation between sputum bacterial load and disease severity in children with Chlamydia trachomatis pneumonia. Methods: C. trachomatis DNA was quantitatively detected by fluorescence quantitative polymerase chain reaction (PCR) sputum from 147 children with C. trachomatis pneumonia. The 147 cases were classified into low load group (<104/mL)

medium load group (from 104 to 106/mL) and high load group (>106/mL). Differences of clinical symptoms

results of chest radiography

duration of mechanical ventilation and length of stay were compared among different groups. Chest radiography were reviewed two weeks after discharge and compared with the results of chest radiography during hospitalization. Results: There was statistically significant difference in the time of shortness of breath among the high load group

the medium load group and the low load group (P<0.01)

yet there was no statistically significant difference between the medium load group and the low load group (P>0.05). There were statistically significant differences in the duration of fever between the high load group and the medium load group (P<0.05)

the high load group and low load group (P<0.01)

yet there was no statistically significant difference between the medium load group and the low load group (P>0.05). There was statistically significant difference in the results of chest radiography among the high load group

the medium load group and the low load group (P<0.05)

yet there was no statistically significant difference between the medium load group and the low load group (P>0.05). There was statistically significant difference in the length of stay among the high load group

the medium load group and the low load group (P<0.001)

yet there was no statistically significant difference between the medium load group and the low load group (P>0.05). There was no significant difference in the duration of mechanical ventilation and number of fever among three groups (P>0.05). After two weeks

the recovery of chest radiography was good

and there was no significant difference among three groups (P>0.05). Conclusion: There is a correlation between the sputum bacterial load of C. trachomatis pneumonia after a certain amount and the clinical characteristics of the child such as time of shortness of breath

duration of fever

severity of chest radiography

and length of hospital stay

but the prognosis is better.

关键词

沙眼衣原体儿童肺炎

Keywords

Chlamydia trachomatischildrenpneumonia

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Clinical Characteristics of Carbapenem-Resistant Enterobacteriaceae in Children with Pneumonia

Changes and Clinical Significance of Interleukin in Serum and Bronchoalveolar Lavage Fluid of Children with Different Pneumonia

Study on the Effect of Popular Science Intervention by Clinical Pharmacists of Traditional Chinese and Western Medicine in Hospitalized Children

Changes of Pathogens and Drug Resistance of Community-Acquired Pneumonia in Children

Distribution Characteristics and Drug-Resistance of Pathogens Isolated from Sputum Culture of Children with Infectious Pneumonia

Related Author

Zhou Mingyuan

Jiang Li

Gui Mingzhu

Wang Junfang

Zeng Na

Yang Qiaoling

Li Zhiling

Shu Wenlin

Related Institution

Jiangsu Xuzhou Central Hospital

Luodian Hospital, Shanghai Baoshan District

Children's Hospital of Shanghai Jiaotong University, Children's Hospital of Shanghai

Xiamen Hospital of Traditional Chinese Medicine

Xingtai Hospital of Traditional Chinese Medicine

⁰